Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypotension
ADR ID BADD_A02216
ADR Hierarchy
24      Vascular disorders
24.06      Decreased and nonspecific blood pressure disorders and shock
24.06.03      Vascular hypotensive disorders
24.06.03.002      Hypotension
Description A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. [CTCAE] Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients. [MeSH]
MedDRA Code 10021097
MeSH ID D007022; D007022; D007022
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Blood pressure low | Chronic hypotension | Hypotension | Hypotension asymptomatic | Hypotension NOS | Hypotension paroxysm | Hypotension symptomatic | Hypotension, unspecified | Hypotensive | Hypotensive episode | Iatrogenic hypotension | Low blood pressure | Low BP | Hypotension aggravated | Acute hypotension | Preshock | Transient systolic hypotension | Arterial hypotension | Vascular Hypotension | Low Blood Pressure | Blood Pressure, Low | Hypotension, Vascular
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Cytochrome P450 2B6P20813T11793
Cytochrome P450 3A4P08684T37848
ReninP00797T61622
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00448Chlorthalidone0.001281%
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00465Cilazapril monohydrate--
BADD_D00466Cilostazol0.000359%
BADD_D00469Cinacalcet hydrochloride--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00473Cisatracurium besylate--
BADD_D00474Cisplatin0.016784%
BADD_D00475Citalopram0.002333%
BADD_D00476Citalopram hydrobromide--
BADD_D00477Citric acid--
BADD_D00479Cladribine--
BADD_D00480Clarithromycin--
BADD_D00481Clemastine fumarate--
BADD_D00482Clevidipine0.000578%
BADD_D00483Clindamycin--
BADD_D00487Clindamycin phosphate--
BADD_D00488Clobazam--
BADD_D00495Clofarabine--
BADD_D00499Clomipramine0.013282%
BADD_D00501Clonazepam0.001293%
BADD_D00502Clonidine0.001952%
BADD_D00504Clopidogrel0.004170%
BADD_D00505Clopidogrel bisulfate--
BADD_D00507Clorazepic acid0.007077%
BADD_D00511Clozapine--
BADD_D00516Codeine--
BADD_D00517Codeine sulfate--
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